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Right here, we explain the characterization of Schistosoma mansoni DHFR (SmDHFR) utilizing isothermal titration calorimetry for the enzymatic task and thermodynamic dedication, additionally the folate analogs inhibition. Additionally, X-ray crystallography was utilized to look for the enzyme atomic model at 1.95 Å.Schistosomiasis caused by parasitic bloodstream flukes associated with genus Schistosoma is an international health

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