https://www.selleckchem.com/pr....oducts/bgb-283-bgb28
The failure of glial cell derived neurotropic factor to be efficacious in blinded clinical trials for Parkinson's disease may be due to alterations in signaling receptors and downstream signaling molecules. To test this hypothesis, brain sections were obtained from older adults with no motor deficit (n = 6), minimal motor deficits (n = 1, and clinical diagnosis of Parkinson's disease (n = 1 who underwent motor examination proximate to death. Quantitative unbiased stereology and densitometry were performed to analyze RET and p
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