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Molecular characteristics, no-cost power computations, volume and residue contact chart analyses had been meant to delineate the explanation for drug-resistance among mutants. We have discovered dihydropteroate synthase (DHPS) as a novel possible therapeutic target for kaempferol. Further researches using molecular characteristics simulations and binding no-cost energies indicate that kaempferol has possible to inhibit perhaps the sulfone-resistant DHPS mutants, rendering it a rather attractiv

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