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In vivo, melatonin reverted LPS-induced cognitive decline, reduced NLRP3 levels and promoted autophagic flux in the hippocampi of WT mice, whereas in α7 nAChR KO mice melatonin effect was not observed. These results suggest that melatonin may modulate the complex interplay between α7 nAChR and autophagy signaling.We introduce the concept of epidemic-fitted wavelets which comprise, in particular, as special cases the number I(t) of infectious individuals at time t in classical SIR models and their derivatives. We present a novel method fo

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