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Our results indicated that the H. vigintioctopunctata lesswright (lwr) gene (Hvlwr) had a 480-bp available reading frame and encoded a 160-amino acid necessary protein. Hvlwr phrase levels were greater in the fat body than other structure types. Hvlwr silencing resulted in better H. vigintioctopunctata mortality rates and were time- and partially dose-dependent, most likely because of the sheer number of hemocytes increasing with dsRNA focus, but decreasing with time. Bacterially expr