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The median decline in eGFR was -1.3 ml/min/1.73 m /year. The incidences of pollakiuria, genital tract infection, urinary tract infection and hypoglycemia were 7.2%, 2.8%, 2.2% and 0.9%, respectively. No participants developed diabetic ketoacidosis during the observation period. SGLT2is improved cardiometabolic parameters in Thai adults, clinically confirming findings in controlled trials. SGLT2is improved cardiometabolic parameters in Thai adults, clinically confirming findings in controlled trials.We herein report two