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Statistical analysis was performed using Statistica 13. A statistically significant difference between groups with various activity of urticaria in D-dimer concentration average values ( 0.05) was observed. Moreover, a statistically significant negative correlation between activity of urticaria and vitamin D concentration ( 0.001) was noted. Our results might support the possible involvement of both coagulation and fibrinolysis pathway and vitamin D in the urticaria pathomechanism. Further prospective studies in larger populatio
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