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The LB cohort had the highest reduction in IOP, compared to the LP and TM cohorts. All treatments had some common adverse ocular effects. Latanoprostene bunod was superior to latanoprost and timolol for the treatment of open-angle glaucoma. Latanoprostene bunod was superior to latanoprost and timolol for the treatment of open-angle glaucoma. The present study was designed to explore the roles of inflammatory cytokines interleukin-1β (IL-1β) and Tumor growth factor-β (TGF-β) in the diagnosis and treatment of neonate bilirubin encephalop