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The serum troponin, LDH, and MDA levels were significantly (p0.01) increased in the MI group compared with the control. Pretreatment with TC before MI induction significantly (p0.01) prevented increased serum troponin, LDH, and MDA levels when compared with the MI group. There was also a significant (p0.01) decrease in MDA in the TC group compared with the control. These results suggest that Theobroma cacao protects against isoproterenol induced myocardial injury, possibly by preventing oxidative stress and consequent lipid