https://www.selleckchem.com/pr....oducts/apr-246-prima
Rheumatoid arthritis (RA) can be initiated and driven by immune responses to multiple antigenic epitopes including those in cartilage proteoglycan (PG, aggrecan) and type II collagen. RA is driven by T helper 1 (Th1) or Th17 pro-inflammatory T cell responses. LEAPS (Ligand Epitope Antigen Presentation System) DerG peptide conjugate vaccines were prepared using epitopes from PG that elicit immune responses in RA patients epitope PG70 (DerG-PG70, also designated CEL-400 and the citrullinated form of another epitope (PG275Cit)
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