https://compoundcinhibitor.com..../novel-substance-het
A myriad of cellular events tend to be regulated by allostery; consequently, advancement of the process is of fundamental interest. Here, we use ancestral sequence reconstruction to resurrect forefathers of two colocalizing proteins, Aurora the kinase as well as its allosteric activator TPX2 (targeting necessary protein for Xklp2), to experimentally characterize the evolutionary road of allosteric activation. Autophosphorylation for the activation cycle is considered the most ancient activation
Like
Comment
Share
