https://www.selleckchem.com/pr....oducts/ldc203974-imt
BACKGROUND Perinatal childhood exposures, including probiotic supplementation, may affect epigenetic modifications and impact upon immune maturation and allergy development. The aim of this study was to assess the effects of pre-and postnatal Lactobacillus reuteri supplementation on DNA methylation in relation to immune maturation and allergy development. METHODS DNA methylation patterns were investigated for allergy-related T helper subsets using a locus-specific method and at a genome-wide scale using the Illumina 450K array.
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