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In vitro, across 15 short-axis measurements with a wide variety of Doppler angles, errors in the flow estimates were below 10% and in vivo, the average velocities in systole obtained from longitudinal (v=69.1 cm/s) and cross-sectional (v=66.5 cm/s) acquisitions were in agreement. Further research is required to validate these results on a larger population.GOAL Low-intensity focused ultrasound stimulation (LIFUS) has the potential to noninvasively penetrate the intact skull and to modulate neural activity in the cortex and deep brain nuc

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