https://www.selleckchem.com/pr....oducts/idasanutlin-r
Multiple brain regions including paraventricular thalamic nucleus (PVT) were activated in familiar observers. The activated cells in PVT contained orexin receptors. Injuring the neurons with ibotenic acid, antagonizing orexin signaling with an anti-orexin antibody or inhibiting neurons by chemogenetic approach in PVT abolished the consolation and anxious behaviors of familiar observers. Conclusions Mice show consolation behavior toward the sick. This behavior attenuates the anxious behavior of surgery mice. The orexin signal
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