https://www.selleckchem.com/pr....oducts/sotrastaurin-
tion is associated with local increases in proteolytic activity that may preferentially weaken and promote rupture at selected regions. We have shown a correlation between flow-mediated ILT deposition with increased tissue levels of MMP-9 activity, increased inflammatory infiltrate, and decreased elastin and collagen content in stereotactically sampled human AAA, suggesting that ILT deposition is associated with local increases in proteolytic activity that may preferentially weaken and promote rupture at selected regions. So
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