https://www.selleckchem.com/ATM.html
Vasculotide (VT), an angiopoietin-1 mimetic peptide, exerts neuroprotective effects in type one diabetic (T1DM) rats subjected to ischemic stroke. In this study, we investigated whether delayed VT treatment improves long-term neurological outcome after stroke in T1DM rats. Male Wistar rats were induced with T1DM, subjected to middle cerebral artery occlusion (MCAo) model of stroke, and treated with PBS (control), 2µg/kg VT, 3µg/kg VT, or 5.5µg/kg VT. VT treatment was initiated at 24h after stroke and administered daily (i.p) for 14days. We evaluated
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