https://www.selleckchem.com/pr....oducts/act001-dmamcl
Autoimmune neutropenia of infancy (AIN) is a frequent cause of neutropenia in children. The disease is caused by antibodies against epitopes on the immunoglobulin G (IgG) Fc receptor type 3b (FcγIIIb). We investigated the possible association of human neutrophil antigens (HNA), human leukocyte antigen (HLA)-DR, and HLA-DQ alleles with AIN and the association of these genotypes with the presence of autoantibodies. Eighty AIN cases with a median age of 13.5months were included. Controls were healthy unrelated Danish blood donors. An