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Topiramate is effective in the prevention of pediatric migraine, and studies show that vitamin D supplementation might also be useful in the treatment of adult migraineurs with a normal vitamin D level. The present study aimed at comparing the efficacy and safety of topiramate plus vitamin D and topiramate alone in the prophylaxis of pediatric migraine. In a single-blinded, randomized, clinical trial, 5-15-year-old children with migraine headaches,referred to the Pediatric Neurology Clinic of Shahid Sadoughi Medical Sciences University, Y