https://www.selleckchem.com/pr....oducts/8-bromo-camp.
Arsenic trioxide (ATO) has been successfully applied in the treatment of acute promyelocytic leukemia (APL). Arsenic metabolites including inorganic arsenic and methylated arsenic could lead to different toxicity and curative effect. This study aims to establish a method to determine arsenic species in red blood cells (RBCs), clarify the distribution characteristics of arsenic species in RBCs. Steady state blood samples were collected from 97 APL patients. H O and HClO were used to release the hemoglobin bounding arsenic and precip