https://www.selleckchem.com/pr....oducts/lirafugratini
Intracranial activity of lapatinib has been demonstrated in several studies in patients with human epidermal growth factor receptor-2 positive breast cancers (HER-2+ BC). Stereotactic radiosurgery (SRS) has been increasingly used as the local therapy for brain metastases in breast cancer patients. Increased objective response rate was observed for lapatinib plus whole brain radiotherapy (WBRT) is such patients with high toxicity. We seek to obtain clinical evidence of synergistic efficacy of lapatinib in combination with radiatio
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