https://www.selleckchem.com/Proteasome.html
Background Among the various orphan G protein-coupled receptors, apelin receptor (APJ), originally identified in the human genome as an orphan G-protein-coupled receptor, was deorphanised in 1998 with the discovery of its endogenous ligand, apelin. Apelin and APJ mRNA are widely expressed in peripheral tissues and the central nervous system in mammals. Objective In this review, we discuss the characteristics, pharmacology, physiology, and pathology of the apelin/APJ system in mammals. Conclusion Several physiological roles of the apelin/APJ s
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