https://www.selleckchem.com/pr....oducts/nor-noha-dihy
loop at 1-month after controlled cortical impact in mice by pharmacological removal of chronically activated microglia using a CSF1R inhibitor, PLX5622. Overall, we show that short-term elimination of microglia during the chronic phase of TBI followed by repopulation results in long-term improvements in neurological function, suppression of neuroinflammatory and oxidative stress pathways, and a reduction in persistent neurodegenerative processes. These studies are clinically relevant and support new concepts that the th
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