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Microsoft Excel and IBM SPSS v 25 were used for data analysis. Results Fifty patients with acromegaly (24 male and 26 females; age range 23-64 years, mean 43) and 200 controls (96 male and 104 females; age range 18-84, mean 42.4) were recruited. 92% (46 out of 5 of patients with acromegaly reported abdominal symptoms and 78% (39 out of 5 had at least one functional gastrointestinal disorder according to the Rome IV diagnostic criteria, compared to 16% of controls (OR 1, P 1, P less then 0.001) as compared to the control group.
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