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Furthermore, diffusivity of biomolecules in the perfusable dual hydrogel system is affected by both the structural and physicochemical properties of the hydrogel system and the microvascular networks formed in the system. The establishment of the dual hydrogel system for vascularization holds great promise as an in vitro angiogenesis model and prevascularization strategy of large tissue constructs.C*06283 differs from C*06020101 by one nucleotide substitution at position 764 in exon 4.Flavoenzymes catalyze oxidations via hydroperoxide