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trauma nurses on the trauma patient experience. To assess the effectiveness of adjuvant analgesics/anesthetics in pain control after separator placement compared with no medication. Separator placement to create space for cementing bands is the first clinical procedure done in orthodontics. Pain in this stage can negatively affect patient compliance and trust in the clinician. To date, there is no universally accepted regimen for pain control. Electronic databases of PubMed, Scopus, and Web of Science were searched. One hundred and th