Mesothelioma Settlements The majority of mesothelioma cases result in settlements, not an outcome by a jury. In , defendants take into account many aspects, including the cost of treatment and lost income. The compensation from a mesothelioma suit can help a victim and their family. Lawsuits also hold those responsible for asbestos exposure accountable. The mesothelioma settlement average is about $1 million. Compensation for Pain and Suffering Compensation may be offered to patients with mesothelioma and their families for pain and suffering