https://www.selleckchem.com/pr....oducts/abc294640.htm
We analyzed the immunohistochemical expression of Ki-67, pRb, Bax, and MMP-9 during the human secondary palate formation (7th to 12th developmental weeks (DWs). The most significant proliferation was observed in the seventh DW with 32% of Ki-67-positive cells in the epithelium, while loose ectomesenchyme condensations (lec) and loose non-condensing ectomesenchyme (lnc) had only 18 and 11%, respectively (Kruskal-Wallis, p less then 0.001), and diminished afterwards. Contrarily, pRb-positive cells were mostly located in the lnc (67%), w