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The debonding strength for group 3 was the highest (5.62 MPa), followed by group 4 (5.20 MPa), then group 2 (0.85 MPa) and finally group 1 (0.0 MPa). The most frequent type of failure was cohesive failure in cement (CC) for all groups, with 73.53% (P ≤ 0.083). Conclusion Er,CrYSGG laser irradiation influences the debonding of lithium disilicate veneers with different thicknesses the smaller thickness showed the greater debonding. The thickness of veneers was not associated with the type of failure.Introduction Attempts to r