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© 2021 Wiley Periodicals LLC. Basic Protocol 1 Tissue handling and cryopreservation of primary and PDTX samples Basic Protocol 2 Performing tumor implant in immunocompromised mice PDTX models Alternate Protocol 1 Intra-medullary femoral injection Alternate Protocol 2 Intravenous injection Alternate Protocol 3 Intraperitoneal injection Support Protocol 1 Phenotypical characterization of PDTXs by flow cytometry Support Protocol 2 Biological and molecular characterization of PDTX tumors by PCR detection of IGK, IGH, and TCR rearrangements
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