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This study aimed to investigate the role of β adrenergic receptor (β AR) in insulin signaling transduction in H9C2 cardiomyoblast cells to understand the formation of the β AR-insulin receptor (IR) protein complex and its role in insulin-induced expression. H9C2 cells were treated with various protein inhibitors (CGP, β AR inhibitor CGP20712; ICI, β AR inhibitor ICI 118,551; PKI, PKA inhibitor myristoylated PKI; PD 0325901, MEK inhibitor; SP600125, JNK inhibitor) with or without insulin or isoproterenol (ISO) before RNA-sequencing (RNA-S

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