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Besides, parameters sensitivity analysis shows that the pest could be controlled at a certain level by choosing suitable parameters.In this paper, we investigate the relationship between the air pollution and tuberculosis cases and its prediction in Jiangsu, China by using the time-series analysis method, and find that the seasonal ARIMA(1, 1, ×(0, 1, 1)12 model is the preferred model for predicting the TB cases in Jiangsu, China. Furthermore, we evaluate the relationship between AQI, PM2.5, PM10 and the number of TB cases, and find that the prediction ac