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ases needed major amputation. 30 day postoperative mortality was 2.5%. Average intervention-free survival was 1626 days (SD ±171, while average amputation-free survival was 2038 days (SD ±1665). Additional intravenous heparin given during thrombolysis did not affect reocclusion rate and amputation-free survival. Catheter-directed thrombolysis is a therapeutic option in acute limb ischemia. Successful thrombolysis often requires endovascular intervention at the same time. Frequent early complications and late reinterventions have to be