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Herein, we discuss the limitations of using neoantigens as goals in HCC immunotherapy and recommend alternate methods to conquer these limitations. Notably, similar limits and alternate strategies are likely relevant to other advanced and reduced tumor mutation burden cancers. This article is safeguarded by copyright laws. All legal rights reserved.BACKGROUND The objective of this research was to analyze the influence of extracorporeal membrane layer oxygenation (ECMO) as a bridge to reoperative

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