https://www.selleckchem.com/pr....oducts/birinapant-tl
Three patients with knee-level complex regional pain syndrome type 1 (CRPS1), recalcitrant to conservative interventions, elected for transfemoral amputation and osseointegration. Two patients gained independent ambulation; the third remains on crutches after a disrupted sciatic nerve targeted reinnervation. One uses no pain medication, one is weaning off, and one requires a reduced regimen after revision nerve innervation. Osseointegration seems suitable to optimize rehabilitation after amputation for CRPS1. Osseointegration
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