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This informative article is safeguarded by copyright laws. All legal rights reserved.BACKGROUND Oocyte activation is driven by intracellular calcium (Ca2+ ) oscillations induced by semen certain PLCζ, abrogation in which causes oocyte activation deficiency in people. Medical PLCζ investigations have-been limited to severe male sterility conditions, while PLCζ levels and localisation habits have yet is related to general sperm viability. MATERIALS AND METHODS P