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High clinical practice variability exists regarding DOAC utilization and urgent reversal strategies in pre-, peri- and post-transplant stages. While more research is needed to refine the clinical landscape, many institutions are using DOAC therapy under the perception that they pose a similar risk of bleeding compared to a non-transplant population. This article is protected by copyright. All rights reserved.The pulmonary blood-gas barrier represents a remarkable feat of engineering. It achieves the exquisite thinness needed fo