https://www.selleckchem.com/pr....oducts/1-deoxynojiri
5 mg. Maximal LH reduction was 70 ± 7% (mean ± sd) at 6 hours after 30 mg SJX-653 versus 10 ± 43% for placebo (P = 0.0006); maximal T reduction was of 68 ± 5% at 8 hours after 60 mg SJX-653 versus 18 ± 11% for placebo (P 0.0001). The plasma IC50 for LH reduction was 33 ng/mL. These data demonstrate clinical proof-of-mechanism for SJX-653 as a potent centrally-acting NK3R antagonist. These data demonstrate clinical proof-of-mechanism for SJX-653 as a potent centrally-acting NK3R antagonist.In artisanal and small-scale gol
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