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The introduction of miR-216a inhibited MPP + -induced neuronal apoptosis. The primary manifestations were the decreased quantities of good price of Tunel cells, caspase 3 task and nucleosome enrichment factor. Bax was a direct target of miR-216a. In inclusion, Bax overexpression reversed the consequences of miR-216a on neural cells. Bax downstream aspects had been additionally involved in miR-216a legislation of MPP + -triggered neuronal apoptosis. miR-216a regulated the development of PD by control