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For α-amylase, there was no significant (P  .05) difference between the K value of acarbose and those of apigenin, cinnamic acid, and rosmarinic acid. The effect of the herbal compounds on cell viability was assessed with the sulforhodamine B (SR assay in C2C12 and HepG2 cells. Acetyleugenol, cinnamic acid, myrcene, piperine, and rosmarinic acid had similar (P  .05) IC values to acarbose. Several of the herbal compounds studied could regulate postprandial hyperglycemia. Using herbal plants has several advantages including low c