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https://www.selleckchem.com/pr....oducts/cdk2-inhibito
Statistical significance was set at p=0.05 level. Of 43 knees, 6 patients had another episodes of SONK (14%), 11 patients were not improving or needed injection vs arthroscopy (26%), 4 patients required arthroplasty (9%), 22 patients had no negative outcome (51%). Gender, age, diabetic status, and location of the subchondral fracture show no influence on outcome. Worse outcome group had a significantly higher average BMI (31.7 vs. 28.0, P=0.02). Positive change of subchondral articular surface contour is the only imaging findi

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