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In a biological synapse, α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors mediate fast excitatory neurotransmission, whereas N-methyl-d-aspartate (NMDA) receptors trigger an enhanced memory effect; the complementary roles of AMPA and NMDA are essential in short-term plasticity (STP) to enhance memory effect (EME) transition. Herein, we report the design and fabrication of the first two-dimensional (2D) conjugated polymer (CP)-based synaptic transistor. The special design of the 2D CP with nanoscale-segregated 'polka

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