https://www.selleckchem.com/pr....oducts/lithium-chlor
In this study, a novel and pullulan-based semi-interpenetrating polymer network gastroretentive microsphere formulation was prepared using the emulsion crosslinking method and optimized by central composite design. The effects of the amounts of glutaraldehyde, , and pullulan on the percent drug entrapment efficiency (EE), percent mucoadhesion at 12 h, and percent drug release at 12 h were optimized. The microspheres were characterized using scanning electron microscopy, fourier transform infrared spectroscopy, and differential