https://www.selleckchem.com/pr....oducts/cabotegravir-
Full-field electroretinograms were severely reduced and the dark-adapted rod and mixed responses were extinguished at earlier visits than the light-adapted cone responses. There was variability in disease severity at the first visit, but results show that the peripheral retina is more susceptible to the deleterious consequences of an mutation. Given the pattern of degeneration and the alternatively spliced isoforms of , potential interventions may consider targeting the periphery early in disease, modulating trans
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