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To demonstrate this, we highlight studies previously published in this journal that show the value of working across scales. We then introduce the six articles that comprise this Focused Topic section. Together, these articles present systems, theory, and methods that provide important insights that could not have been obtained from studying a single scale in isolation.AbstractMany pathogens reside in environmental reservoirs within which they can reproduce and from which they can infect hosts. These facultative pathogens experience di

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