https://www.selleckchem.com/products/vvd-214.html
Tacrolimus is a critical dose drug and to avoid under- and overexposure, therapeutic drug monitoring is standard practice. However, rejection and drug-related toxicity occur despite whole-blood tacrolimus pre-dose concentrations ([Tac] ) being on target. Monitoring tacrolimus concentrations at the target site (within peripheral blood mononuclear cells; [Tac] ) may better correlate with drug-efficacy. The aim of this study was to (1) investigate the relationship between [Tac] and [Tac] , (2) identify factors affecting the tacrolimus dist