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Furthermore, adropin therapy dose-dependently increased the phosphorylation standard of AMP-activated protein kinase (AMPK). Suppression of AMPK by substance C or AMPKα1 siRNA blocked adropin-induced decreases in the mature kind of SREBP-1c expression, glucose result, and intracellular triglyceride content in OA-treated hepatocytes. These results claim that teleost adropin could suppress hepatic gluconeogenesis and triglyceride buildup via a mechanism determined by AMPK signalling.Progesterone and

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