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Nonetheless, the majority of the reported agents are Gd-based products that display nephrotoxicity, and few research reports have centered on Fe-based products due to their reduced relaxivity. This work describes the development of an ellagic acid (EA)-Fe nanoscale coordination polymer with high longitudinal relaxivity and powerful near-infrared absorption for dual-modality T1-weighted MRI and photoacoustic imaging. The longitudinal relaxivity (r1) of the prepared EA-Fe@BSA nanoparticles was 2.54 mM-1 s-1,

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