https://www.selleckchem.com/pr....oducts/stat-in-1.htm
A variety of ultrastructural abnormalities were discovered in silica-exposed airway cilia, including absence of central pair microtubules, disorganized microtubules and clusters of axoneme on day 1 and 7. The numbers of ciliary axonemes and basal bodies in ciliated epithelial cells were significantly decreased, whereas the proportion of abnormal axonemes was gradually increased with exposure to silica particles (P less then 0.05). In addition, silica particles significantly decreased MUC5B expression on the surface of airway epithel
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