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The lowest success rates were observed for the volatile fatty acid (VFA) concentration in the digestate. Despite the lack of available data and the number of assumptions that had to be made, the model was demonstrated to be capable of reproducing the behavior of the full-scale reactors. A proper, up-to-date, calibrated and validated model can aid in the decision-making process in a WRRF, for instance, in determining some unmeasured inlet conditions, in improving the resilience of the process and in managing the incorporation of a new c