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Currently, scientists around the world are focusing their particular attention to the growth of novel particles to deal with migraines by targeting the CGRP receptor, that can easily be attributed to its specificity one of the several proteins taking part in migraine. Granulocyte colony-stimulating element (G-CSF) expressed in engineered Escherichia coli (E. coli) as a recombinant protein is used as an adjunct to chemotherapy for improving neutropenia. Recombinant proteins over

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